St Dominic's College was begun in 1965 under the Catholic administration of St Dominic's Forane Church, Kanjirappally, to oblige the higher instructive needs of the area specifically, and of the eastern pieces of the Archdiocese of Changanacherry all in all. This was the satisfaction of a long-felt need of this district which was one of the instructively in reverse territories in Kerala. At the point when the new Diocese of Kanjirappally was shaped in 1977, St Dominic's College expected the interesting differentiation of being the main organization offering advanced education in the entire bishopric. The school likewise incorporates into its domain the scholarly yearnings of the non-Catholic people group of the region and is focused on giving training to all who look for higher learning at these entryways, independent of station, statement of faith and network. This focal point of learning keeps to its greatest advantage the erudite person, social and good progression of the entire zone. Consistent with the saying "Dread of God is the start of knowledge", the school attempts to ingrain in the hearts of its understudies trust in God and confidence in moral and otherworldly qualities. It targets maintaining the most noteworthy Christian standards alongside scholastic perfection. The College targets making its understudies live its witticism 'Ingest and Radiate'- ingest the light of information and values and transmit what they assimilate, in this way extending the wildernesses of truth and astuteness.